Nutrition, obesity and diabetes

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Location of perilipin and caveolin protein
Location of perilipin protein around lipid droplets, in green and caveolin protein, in red via immunofluorescence in murine fat cells of the cell line 3T3-L1. Perilipins play a role in the fat cell release of glycerol and fatty acids such as insulin and noradrenaline. Caveolin is the major protein of the caveola involved in the homeostasis of cell cholesterol. Image created at the Cordeliers Research Center, team 8, Paris.

 

Location of perilipin protein
Marking of perilipin protein located around lipid droplets, in green and nucleuses, in blue on a section of murine fatty tissue via immunofluorescence. Perilipins play a role in the fat cell release of glycerol and fatty acids such as insulin and noradrenaline. Image created at the Cordeliers Research Center, team 8, Paris.

 

Fat cells
Lipid droplets of fat cells. Image created at the Cordeliers Research Center, team 7, Paris.

 

Coloring of lipids
Coloring of neutral lipids via Oil Red O stored in lipid droplets of fat cells of the murine cell line 3T3-L1. Image created at the Cordeliers Research Center, team 8, Paris.

 

Coloring of lipids
Coloring of neutral lipids via Oil Red O stored in lipid droplets of fat cells of the murine cell line 3T3-F442A. Image created at the Cordeliers Research Center, team 8, Paris

 

Location of the GLUT4 receptor
GLUT4 is the glucose transporter which allows for the captation of the circulating glucose by the muscles and fatty tissue in response to the insulin. Image created at the Cordeliers Research Center, team 7, Paris.

 

Pancreatic islet
Immunofluorescence marking for GLUT2, in green and the insulin, in red on a section of rat pancreas. GLUT2 is one of the glucose transporters. It is a major isoform in islet cells of the pancreas allowing for a synthesis and a secretion of insulin that is adapted to the glycemia. Image created at the Cordeliers Research Center, team 8, Paris.

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