Brain: corpus callosum

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Organization of the corpus callosum

Organization of the corpus callosum
Detail of a coronal section of the corpus callosum of a wild mouse brain. The corpus callosum is a cerebral structure formed by a bundle of neural fibers from the two cerebral hemispheres. In red: fibers of the corpus callosum marked by the protein L1CAM; in green: fibers marked by the Neuropilin-1 receptor; in blue, the nuclei.

 

Disorganization of the corpus callosum when the guidance protein Semaphorin-3A is not present

Disorganization of the corpus callosum when the guidance protein Semaphorin-3A is not present
Coronal section of the corpus callosum of a mouse brain invalidated for the guidance protein Semaphorin-3A, multiplied by 4 (artistic montage). In red: fibers of the corpus callosum marked by the L1CAM protein; in green: fibers marked by the Neuropilin-1 receptor; in blue: the nuclei.

 

Organization of the corpus callosum

Organization of the corpus callosum
Corpus callosum of a wild mouse brain. The corpus callosum is a cerebral structure formed by a bundle of neural fibers from the two cerebral hemispheres. In red: fibers of the callous corpus marked by the L1-CAM protein; in green: fibers marked by the Neuropilin-1 receptor; in blue, the nuclei.

 

Disorganization of the corpus callosum when the guidance protein Semaphorin-3A is not present

Disorganization of the corpus callosum when the guidance protein Semaphorin-3A is not present
Detail of a coronal section of the corpus callosum of a mouse brain invalidated for the guidance protein Semaphorin-3A. The corpus callosum is a cerebral structure formed by a bundle of neural fibers from the two cerebral hemispheres. The fibers marked by the receptor Neuropilin-1 (green) are disorganized in the mutant of the guidance protein Semaphorin-3A unlike in the wild one. In red, fibers of the callous corpus marked by the L1CAM protein; in blue, the nuclei.

 

Unbundling of the corpus callosum when the guidance protein Semaphorin-3A is not present

Unbundling of the corpus callosum when the guidance protein Semaphorin-3A is not present
Coronal section of the corpus callosum of a mouse brain invalidated for the guidance protein Semaphorin-3A. The corpus callosum is a cerebral structure formed by a bundle of neural fibers from the two cerebral hemispheres. The fibers marked by the receptor Neuropilin-1 (green) are unbundled in the mutant of the guidance protein Semaphorin-3A unlike the wild one. In red, fibers of the callous corpus marked by the L1CAM protein; in blue, the nuclei.

 

Organization of the corpus callosum

Organization of the corpus callosum
Coronal section of the corpus callosum of a mouse brain, multipled by 4 (artistic montage). In red: fibers of the callous corpus marked by the L1CAM protein; in green: fibers marked by the Neuropilin-1 receptor; in blue: the nuclei.

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