Clinical Investigation Centres (CIC) are clinical research infrastructures available to investigators for carrying out their projects in clinical and health research. These may be projects aimed at better understanding a disease, and inspired by results of work done in research laboratories, e.g. at Inserm. They may also be projects to test new treatments.
The Clinical Investigation Centres (CIC) are governed by a joint authority, i.e. the Directorate-General for Care Provision (DGOS) of the Ministry of Health and Sport, and Inserm. There are 36 CIC sites with 54 units located within the university hospitals.
Multi-theme CIC units: structures equipped with hospital beds and technical research equipment, with nursing staff specially trained and qualified in good clinical research practice. These structures ensure the safety of people volunteering for research, as well as the quality of the research. The multi-theme units conduct studies on new drugs, or studies in physiopathology. They offer researchers the skills and resources needed to perform research on healthy volunteers and patients.
“Clinical Epidemiology” CIC units: methodological structures supporting clinical and epidemiological research. Established in order to create and monitor cohorts, major clinical investigations and clinical trials, these CIC offer investigators methodological and biostatistical solutions for their projects, along with logistical support from professionals.
“Technological Innovation” CIC units: structures devoted to the evaluation and innovation of biomaterials, medical devices, specialised health-related software, etc. Used for diagnosing, treating or monitoring certain diseases, these structures are open to pharmaceutical and other companies for preliminary advice on regulations and the best approach to innovation. They provide evaluations using technical resources and methodological tools tailored to the projects. They also have a role in incubating start-up companies, in partnership with the technology parks.
“Integrated Biotherapy” CIC units: they conduct innovative research programmes, especially in cell and gene therapy, immunotherapy, and vaccination.
The CIC also have a role in training physicians, pharmacists and paramedical staff in clinical and health research, and a role in driving clinical research in the university hospital.